Automated Online Desorption and Analysis of DNPH Derivatives of Formaldehyde, Acetaldehyde, and Related Carbonyl Compounds using a New Robotic Autosampler

Fredrick D. Foster, Jacqueline Whitecavage, Kurt Thaxton, John R. Stuff

Abstract

The analysis of airborne aldehydes and ketones fi rst involves collection of the analytes by passing air through a cartridge containing 2,4-dinitrophenylhydrazine (DNPH). As the air passes through the cartridge, the analytes react with the DNPH to form hydrazones which are immobilized on the cartridge. The cartridges are then eluted with solvent and the DNPH derivatives can be determined using HPLC with UV detection.