Enhanced characterisation of cannabis extracts using flow-modulated GC×GC– TOF MS/FID with Tandem Ionisation

This study demonstrates the use of flow-modulated GC×GC to analyse complex cannabis extracts, with simultaneous detection by TOF MS for confident identification and FID for robust quantitation. GC×GC provides the enhanced separation necessary to enable a wide range of components, including cannabinoids, terpenoids and pesticides, to be analysed in a single analytical run, while Tandem Ionisation adds an additional level of confidence for compounds exhibiting weak molecular ions and/or similar spectra at 70 eV.