Subscribe to Newsletter

Dynamic light scattering used in polymer nanoparticle characterization

Introduction

Polymer Nanoparticles

Polymer nanoparticles have been widely studied as possible drug delivery systems due to their ability to control the release of drug contained within them and due to their biocompatibility [1,2]. They are relatively easy to produce with their drug release profiles dependent upon polymer structure. Some of the important characteristics of polymer nanoparticles for drug delivery applications include their particle size and surface chemistry. Typically, they range in size from 10 to 1000nm in diameter allowing them to transverse cell membranes.

There are a variety of ways in which delivery of encapsulated drug from polymer nanoparticles can be controlled [1]. These include physical (e.g. sonorphoresis), chemical (e.g. pH, salt concentration), biochemical (e.g. enzyme) and environmental (e.g. temperature) mechanisms. The influence of these mechanisms on the size of the polymer nanoparticles can be investigated using dynamic light scattering (DLS).

Read the full article now

Log in or register to read this article in full and gain access to The Analytical Scientist’s entire content archive. It’s FREE!

Login
Receive content, products, events as well as relevant industry updates from The Analytical Scientist and its sponsors.
Stay up to date with our other newsletters and sponsors information, tailored specifically to the fields you are interested in

When you click “Subscribe” we will email you a link, which you must click to verify the email address above and activate your subscription. If you do not receive this email, please contact us at [email protected].
If you wish to unsubscribe, you can update your preferences at any point.

Register to The Analytical Scientist

Register to access our FREE online portfolio, request the magazine in print and manage your preferences.

You will benefit from:
  • Unlimited access to ALL articles
  • News, interviews & opinions from leading industry experts
  • Receive print (and PDF) copies of The Analytical Scientist magazine

Register