Tosoh

Combining FcR-IIIA affinity separation with HILIC-MS analysis allows rapid screening of antibodies

A Robust Method for In-Depth Sample Characterization.

A Revolutionary Technology for Macromolecular Characterization.

Viruses and virus like particles (VLPs) are multimeric protein structures that mimic native viruses but are non-infectious.

Light scattering detection (LS) is a widely used technique to obtain the “absolute” or true molecular weight of macromolecules.

Light scattering of macromolecules in solution has seen increasing interest over the past decades from scientists studying polymers and proteins.

Antibody-dependent cell-mediated cytotoxicity (ADCC) is an important mechanism of action (MoA) of monoclonal antibodies used in cancer treatment.

Fc-glycans of therapeutic antibodies are known to play an important role in the recognition of antibodies by the FcγIIIa receptor.

Biotherapeutics are generally larger molecules such as peptides, proteins and monoclonal antibodies

Today new antibody formats are entering clinical phases some of which are larger than conventional mAbs