When is a glass of milk not a glass of milk? When it’s an adulterated glass of milk.


In our September cover feature – “Piracy in the Pantry” – we speak to the FDA about the analytical techniques used to catch food fraudsters and how they are keeping consumers (like you and I) safe from increasingly sophisticated adulteration. Also in this week’s newsletter: a look at the use of GC×GC coupled with high-resolution MS in breathomics research, Ron Majors and John Baltrus reflect on the last 50 years of HPLC and choose their Top 10 breakthroughs in the technique’s development, and we learn how X-ray free-electron lasers could enable imaging of atomic-scale structures. Enjoy!

Lauren Robertson, Deputy Editor

The Ultimate Untargeted Technique
09/05/2020 | Pierre-Hugues Stefanuto, Delphine Zanella, Jean-François Focant
Could the linking of GC×GC with high-resolution MS prove key to improved resolution in breathomics?
Piracy in the Pantry
09/04/2020 | Matthew Hallam
Food adulteration puts public health – and lives – at risk. We spoke to the FDA to find out how they're protecting citizens.
The Top 10 Game Changers in HPLC History
09/10/2020 | Ron Majors, John Baltrus
We look back on the first 50 years of HPLC instrumentation and select the key breakthroughs that paved the way for the technique we know today.
Mirror, Mirror Focus Small
09/09/2020 | Lauren Robertson
Researchers move closer to imaging atomic-scale structures using ultraprecise mirrors and X-ray free-electron lasers
MALS Technology for next generation biopharmaceuticals

On September 23, The Analytical Scientist will be hosting a webinar with Tosoh about the fundamentals (and benefits) of multi-angle light scattering (MALS) detection for the analysis of macromolecules. Find out more

Elevate your quantitative and qualitative LC-MS pesticide analysis

Discover how you can improve sample throughput and have increased confidence in your quantitation and identification of pesticide residues in food by joining our webinar with Thermo Fisher Scientific on September 30. Find out more

Protein Footprinting Applications in Structural Biology

Join our webinar with NeoProteomics and GenNext Technologies on October 14 to discover the value of protein footprinting in biopharmaceutical research. Find out more

Application Notes
EmporeTM Oil & Grease SPE Disk for EPA 1664 with 40% n-hexane consumption

CDS EmporeTM (formerly 3MTM EmporeTM) Oil and Grease SPE disk under EPA Method 1664 is demonstrated to reduce the total volume of n-hexane by 40% while maintaining the same recovery rates. Read more

PharmaFluidics’ µPAC™, a new era in LC column-to-column reproducibility

Due to superior microfabrication, sub second RT variation was achieved across 3 different μPAC™ columns. CV values down to 0.24% highlight the unique potential for standardizing analytical procedures. Read more

Improved Hydrocarbon Fractionation Using UCT’s Novel Silver-Phase SPE Sorbent

This application note outlines a new specialized SPE sorbent, Fusion® Ag+, designed to help overcome the challenges associated with traditional silica gel EPH fractionation. Read more

Extraction of a Comprehensive Steroid Panel from Human Serum via Microelution Plates

This application details the extraction of steroid hormones from human serum using Biotage® Mikro ABN microelution plates prior to LC/MS-MS analysis, delivering clean extracts & improved recoveries. Read more

Gene Therapy Research Characterization Using DLS and Zeta Potential

Zeta potential measurements are being used to develop the most efficient formulations of liposomes, peptides, DNA complexes for transfection studies in vivo and in vitro. Read More.

Using the Power Law Model to Quantify Shear Thinning Behavior on a Rotational Rheometer

A material’s rheological properties not only influences its visual and textural perception, but also affects its processing capabilities. Read More.

Product Profiles
Genius XE Nitrogen Generator: When only exceptional will do

Built upon decades of innovation in gas generation for the lab, Genius XE nitrogen generator is a cutting-edge evolution combining advanced technology with refined and robust engineering. Read more

MALDImini-1: Entering the digital age in MS

The first-of-its-kind MALDImini-1 digital ion trap mass spectrometer targets comprehensive structural analyses applications. It is the only device capable of MALDI-MSn on the compact footprint of an A3-sized paper. Read more

Special Promotions
From The Cannabis Scientist team comes a dedicated cannabis + cannabinoid science newsletter

A weekly digest bringing you the latest discoveries, analytical advances, and business updates in the cannabis + cannabinoid science sector in a 5-minute read. Sign me up now

Events to Watch Out for in 2020

We work with event organizers from all around the world to help bring the analytical science community together, from large congresses to intimate meetings that fit around a table. Discover some of the events that we partner with and and stay up-to-date with the latest developments.

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