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The Analytical Scientist / App Notes / 2020 / Enabling new levels of quantification

Enabling new levels of quantification

11/11/2020

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The ability to achieve high levels of sensitivity while retaining quantitative performance is key to achieving robust analytical results. The growing number of demanding workflows requiring reliable quantification of more analytes per assay, in increasingly complex matrices, highlights the need for a sensitive MS instrument capable of providing the high level of performance that can meet these analytical challenges. The SCIEX Triple Quad™ 7500 LC-MS/MS System – QTRAP Ready is enabling new levels of quantification across a large suite of sample types and workflows. The greater sensitivity is achieved through the introduction of hardware features that enable significant gains in the generation, capture and transmission of ions.

Improvement in the efficiency of ion capture and transmission is because of the D Jet™ Ion Guide, which achieves greater sensitivity by sampling more ions, and without sacrificing robustness. Improved ion generation and sampling is accomplished through better desolvation, achieved by the addition of the E Lens™ Technology that delivers more sensitivity in ESI by increasing the field strength experienced by the ESI droplets. The versatility of the OptiFlow® Pro Ion Source provides the ability to analyze a wide range of compounds by seamlessly switching between ESI and APCI mode. In addition, the modular architecture of the source enables users to change flow rates by simply changing probes and electrodes in the source. This improved versatility enables users to achieve the best sensitivity under all conditions, future proofing labs for future innovations across many different applications.

>> Download the Full Application Note as a PDF

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