The Analytical Scientist

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The Coffee Break: With James Grinias

By James Strachan

April 30, 2026

Jim Grinias shares the ideas and debates shaping conference conversations – from AI to interdisciplinary science

7 min read

Omics Metabolomics & Lipidomics News & Research Mass Spectrometry Trends & Challenges

The Missing Piece in the Dark Metabolome Puzzle?

By James Strachan

April 8, 2026

Microdroplets formed during electrospray ionization may trigger chemical reactions that help explain a substantial portion of the “dark metabolome” – though some researchers question their relevance under typical metabolomics conditions

7 min read

The Missing Piece in the Dark Metabolome Puzzle

Mass Spectrometry Environmental Trends & Challenges Food, Beverage & Agriculture Metabolomics & Lipidomics

The Past, Present and Future of Non-Target Screening

March 23, 2026

Thomas Letzel reflects on the evolution of non-target screening and why interdisciplinary insights are key to its future

6 min read

The Past Present and Future of Non-Target Screening

Omics Omics Trends & Challenges Mass Spectrometry

CSF Proteomics Identifies New Biomarkers for Multiple Sclerosis

March 11, 2026

Large-cohort CSF proteomics from the Mann Lab identifies a 22-protein panel distinguishing MS from related diseases

2 min read

CSF Proteomics Identifies New Biomarkers for Multiple Sclerosis

Environmental Sensors Trends & Challenges

Portable Sensors: The Next Generation of PFAS Detection

By James Strachan

March 11, 2026

Silvana Andreescu on the urgent need for low-cost, field-deployable PFAS sensors

7 min read

Portable Sensors: The Next Generation of PFAS Detection

Environmental Environmental Trends & Challenges

Confronting the Messy Reality of PFAS Regulation

By James Strachan

March 4, 2026

David Megson calls for joined-up thinking, smarter analysis, and stronger partnerships between academia, industry, and government

9 min read

Confronting the Messy Reality of PFAS Regulation

Environmental Mass Spectrometry Trends & Challenges Clinical

PFAS Bioaccumulation: The Biology of Forever

February 23, 2026

Carrie McDonough explores how PFAS move, bind, and transform within us – redefining what exposure really means

13 min read

PFAS Bioaccumulation The Biology of Forever

Pharma and Biopharma Pharma & Biopharma Trends & Challenges Liquid Chromatography

GLP-1 Analysis: Riding the Wave of Peptide Innovation

By Amanda M. Guiraldelli, Piotr Alvarez, Koen Sandra

January 26, 2026

The remarkable commercial success of GLP-1 receptor agonists is fueling investment, accelerating science, and creating new analytical challenges. Here, we outline the hurdles these peptides present, explore methods for impurity profiling and structural characterization, and consider strategies to keep pace with this fast-moving field.

12 min read

GLP1 Analysis Riding the Wave of Peptide Innovation

Mass Spectrometry Metabolomics & Lipidomics Trends & Challenges Data & AI Opinion & Personal Narratives

Lighting the Way Forward for Metabolomics

By Alexander Makarov, Bashar Amer, Susan S. Bird, ..et al.

December 15, 2025

Advanced software tools and self-correcting instruments could soon put the dark metabolome debate to bed, argue Alexander Makarov and the Thermo Fisher Scientific team

4 min read

Lighting the Way Forward for Metabolomics

Data and AI Metabolomics & Lipidomics Translational Science Mass Spectrometry Trends & Challenges

Accelerating Biomarker Discovery with AI-Enhanced Omics

By Henry Thomas

December 11, 2025

By fusing multi-omics data with AI, Sapient Founder Mo Jain believes researchers will close the gap between molecular measurement and clinical meaning

10 min read

Accelerating Biomarker Discovery with AIEnhanced Omics

Mass Spectrometry Chromatography Spectroscopy Microscopy Sensors Data & AI Clinical Environmental Food, Beverage & Agriculture Pharma & Biopharma Omics Forensics

Trends & Challenges

The Coffee Break: With James Grinias

The Missing Piece in the Dark Metabolome Puzzle?

The Past, Present and Future of Non-Target Screening

CSF Proteomics Identifies New Biomarkers for Multiple Sclerosis

Portable Sensors: The Next Generation of PFAS Detection

Confronting the Messy Reality of PFAS Regulation

PFAS Bioaccumulation: The Biology of Forever

GLP-1 Analysis: Riding the Wave of Peptide Innovation

Lighting the Way Forward for Metabolomics

Accelerating Biomarker Discovery with AI-Enhanced Omics

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