The Analytical Scientist

Omics Translational Science Genomics & DNA Analysis Proteomics Data & AI Mass Spectrometry News & Research

Mapping Missense Mutations with Proteogenomics

By Henry Thomas

September 16, 2025

Using SILAC mass spectrometry and mutation databases, researchers uncover how missense variants reshape protein abundance in prostate cancer

3 min read

Mapping Missense Mutations with Proteogenomics

Metabolomics & Lipidomics Data & AI Liquid Chromatography Metabolomics & Lipidomics News & Research

How Mutations Affecting Purine Metabolism Shaped the Human Brain

September 11, 2025

Mouse models with human-specific ADSL variants have sex-specific effects on brain function

4 min read

How Mutations Affecting Purine Metabolism Shaped the Human Brain

Data and AI Liquid Chromatography Technology Keynote Interviews

When Does an Instrument Become a Collaboration Partner?

September 11, 2025

Agilent’s Christian Haas on the changing role of analytical instruments in the age of automation

4 min read

When Does an Instrument Become a Collaboration Partner

Mass Spectrometry Sensors Omics Technology Data & AI

Welcome to the Era of Megadaltons… and Beyond…

By Henry Thomas

September 4, 2025

As new ion sources and megadalton capabilities emerge, the boundaries of mass spectrometry are being redefined, suggests David E. Clemmer from Indiana University

8 min read

Welcome to the Era of Megadaltons and Beyond

Proteomics Translational Science Data & AI Microscopy News & Research

Protein Mapping at Subcellular Resolution

August 26, 2025

By clustering protein signatures at the pixel level, PathoPlex offers a new perspective on tissue pathology and disease mechanisms

4 min read

Protein Mapping at Subcellular Resolution

Mass Spectrometry Data & AI Trends & Challenges Environmental

Drowning in Features; Thirsty for Answers

By Henry Thomas

August 26, 2025

The challenge of identifying unknowns looms large for mass spectrometry, says Susan Richardson, who returned from ASMS 2025 with new ideas – and a hope that AI might finally bridge the gap between data and discovery

8 min read