Challenging Task
The use of 100% water as an eluent has been a challenge in HPLC separation for decades. Even today, many C18 materials suffer from unacceptable short lifetime, as a result of the C18 chains collapsing which reduces the separation performance drastically. As a pioneer in the field of aqueous compatible phases, YMC has offered suitable products since the 80’s for stability under aqueous conditions.
Solution
Ability to work with 100% aqueous conditions opens the door to extend the purification range to include polar compounds efficiently and economically. Due to their equivalent selectivity processes can be easily scaled up from analytical to preparative scale. Furthermore, desalting can be performed using RP-C18 phase to reduce one step within the downstream processing. YMC-Triart Prep combines high mechanical strength with chemical stability to ensure robust, long-lasting and economic purifications.
>> Download the full Application Note as PDF
Newsletters
Receive the latest pathologist news, personalities, education, and career development – weekly to your inbox.
