Light scattering detection (LS) is a widely used technique to obtain the “absolute” or true molecular weight of macromolecules such as synthetic polymers, biopolymers, proteins, and antibodies. When coupled with size exclusion chromatography (SEC), molecular weight and size, as well as aggregation or branching can be investigated to provide analytical scientists with a powerful characterization tool for these large molecules.
Whether new biopharmaceutical products or polymers with tailored properties, the macromolecules’ complexity increases, requiring even more extensive and in-depth characterization for a full understanding of the material. With limited amounts of costly samples available for analysis, analytical scientists are facing the challenge of finding new technologies that help them improve and optimize their analytical characterization.
The latest light scattering technology introduced by Tosoh Bioscience features an entirely new detector design that addresses the limitations and shortcomings of the current, state-of-the-art LS instruments.
>> Download the Full Application Note as a PDF
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