Built specifically for small molecule analysis, the Thermo Scientific™ Orbitrap IQ-X™ Tribrid™ MS utilizes technology that significantly augments unknown analysis capabilities in metabolite identification (Met-ID), untargeted metabolomics, and lipidomics research, but also shows benefits for structural elucidation of oligonucleotides and natural products research. The information provided here describes the technologies that set the Orbitrap IQ-X Tribrid MS apart from other instrumentations including previous generation Thermo Scientific™ Orbitrap ID-X™ Tribrid™ MS, Thermo Scientific™ Orbitrap Exploris™ platform, Thermo Scientific™ Q Exactive™ instruments, and quadrupole time-of-flight (QTOF) mass analyzers.
Thermo Scientific™ Orbitrap™ Tribrid™ mass spectrometers are an essential tool for high-end life science research. Equipped with a combination of the best of quadrupole, linear ion trap and ultrahigh resolution Orbitrap mass analyzer that deliver acquisition of the richest MSn data. This unique hardware combination provides superior analytical performance that enables multiple modes of analysis due to the parallel isolation and detection of ions, which is not available with on Orbitrap Hybrid mass spectrometer or QTOF instrumentation. The Orbitrap IQ-X Tribrid MS (Figure 1) has been specifically designed to unravel complex chemical structures while delivering the highest versatility and comprehensive workflow support for analysis of small molecule unknowns. This became possible with the recent advances in mass spectrometry technology including real-time spectral library search, multiple fragmentation techniques, higher precursor ion selectivity and a fully automated calibration source.
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