Like most websites The Analytical Scientist uses cookies. In order to deliver a personalized, responsive service and to improve the site, we remember and store information about how you use it. Learn more.
Subscribe to Newsletter
Techniques & Tools Liquid Chromatography

A New Era in LC Column-to-Column Reproducibility

Jeff Op de Beeck, Geert Van Raemdonck and Paul Jacobs

The importance of establishing robust and reliable analytical methods is of paramount importance in today’s life science research and the (bio) pharmaceutical industry. Liquid chromatography (LC), e it h e r coupled with UV detection or mass spectrometry has a prominent position within biomarker discovery and quality control workf lows. Among other factors, the quality of the LC column has a significant impact on the data reproducibility and thus the method robustness. LC columns are typically fabricated by packing spherical silica particles into a cylindrical column. Even though column technology has improved enormously in the past decades, batchto-batch repeatability is still a critical issue that can have a serious impact on LC workflow robustness. By using an entirely different LC column fabrication process, PharmaFluidics brings an extremely robust alternative to the LC column market, called micro Pillar Array Columns (µPAC™).

Read the full article now

Log in or register to read this article in full and gain access to The Analytical Scientist’s entire content archive. It’s FREE!

Receive content, products, events as well as relevant industry updates from The Analytical Scientist and its sponsors.
Stay up to date with our other newsletters and sponsors information, tailored specifically to the fields you are interested in

When you click “Subscribe” we will email you a link, which you must click to verify the email address above and activate your subscription. If you do not receive this email, please contact us at [email protected].
If you wish to unsubscribe, you can update your preferences at any point.

Related Application Notes
Instrumental Analysis to Visualize Differences in Taste

| Contributed by Shimadzu

Analysis of mRNA coupled to enhanced green fluorescent protein by RP and IEX

| Contributed by YMC

Analysis of Aroma for Beverage Quality Control

| Contributed by Shimadzu

Related Webinars
Techniques & Tools Spectroscopy
The Analytical Spectroscopy Technology Forum

| Sponsored by WITec GmbH, Bruker Optics, Hamamatsu Photonics Europe GmbH, and DRS Daylight Solutions

Techniques & Tools Liquid Chromatography
The Next-Level LC-MS Technology Forum

| Sponsored by ACD Labs, Agilent, Tosoh and Andrew Alliance (Waters)

Techniques & Tools Thin Layer Chromatography
Comprehensive HPTLC Fingerprinting for Quality Control of Herbal Drugs

| Sponsored by CAMAG

Most Popular
Register to The Analytical Scientist

Register to access our FREE online portfolio, request the magazine in print and manage your preferences.

You will benefit from:
  • Unlimited access to ALL articles
  • News, interviews & opinions from leading industry experts
  • Receive print (and PDF) copies of The Analytical Scientist magazine