Advanced high throughput biotherapeutic glycosylation profiling with ion mobility
The MOBIE platform improves speed, resolution & analysis in LC mass spectrometry. Increase throughput while maintaining data quality plus simplified automated data analysis.
contributed by MOBILion Systems Inc |
As mass spectrometry instrumentation becomes faster and more sensitive, overall method time, resolution and depth of analysis are now limited by separation methods. To enhance overall front-end separatory techniques, post-ionization gas-phase separations have become more common in conjunction with traditional liquid separations prior to mass analysis. The use of ion mobility-mass spectrometry (IM-MS) can significantly reduce analysis times and improve resolution of glycan isomers compared to LC-MS alone. IM-MS platforms have become commercially available and the importance of this additional dimension of separation is now being realized in industry settings.
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