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Analysis of 26 Natural and Synthetic Opioids in Blood and Urine Using Clean Screen® DAU SPE and a Selectra® DA UHPLC Column


In recent years, drug abuse has become one of the leading causes of accidental deaths across the country. The opioid crisis was one of the main manifestations of drug-related addictions that caused severe dependency and, in too many cases, fatal overdoses. In this application note, UCT offers a simple yet effective procedure to extract and monitor an extensive panel of opiates in blood and urine using solid-phase extraction (SPE) combined with ultra-high performance liquid chromatography coupled to tandem mass spectrometry (UHPLCMS/MS). Clean Screen® DAU is UCT’s flagship SPE cartridge that can be used to extract a wide range of natural and synthetic opioids with excellent recoveries and overall precision.

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