Cannabis sativa is well-known for its use as a recreational drug due the presence of the psychoactive compound tetrahydrocannabinol (THC), and has been listed as a Schedule 1 drug in the United States since the passage of the Controlled Substances Act of 1970.1 With the recent surge in legalization of recreational and medicinal use, there is a need for reliable analytical tools to meet the regulatory requirements for pesticide testing in Cannabis. Action limits for each pesticide vary between jurisdictions, but can be as low as 10 ppb.2,3
The JEOL JMS-TQ4000GC triple-quadrupole GC-MS/MS system offers high speed and high sensitivity for quantitation of trace or residual pesticides. The TQ4000 combines a unique short collision cell with JEOL’s patented ion accumulation and timed detection technology to provide high sensitivity and selectivity, as well as the fastest selected reaction monitoring (SRM) switching speed available (up to 1000 transitions per second). JEOL msPrimo and Escrime software provide all of the tools needed to develop optimized methods for target compound quantitation and report generation. In this application note, we describe a sensitive method for analyzing pesticides in Cannabis sativa matrix using the SRM capabilities of our triple quadrupole system.
>> Download the Full Application Note as a PDF
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