Analysis of Pharmaceuticals in Water Using Automated On-line SPE-LC-MS/MS

contributed by Biotage | 09/05/2016

This application note describes the use of EVOLUTE^® EXPRESS ABN on-line cartridges for extraction of 13 commonly prescribed pharmaceuticals in water. This is an automated on-line SPE-LC-MS/MS method where the SPE is fully integrated into the analytical workflow.

The analytical challenge of measuring emerging contaminants in the environment has been a major research focus of scientists for the last 20 years. Pharmaceuticals and personal care products are an important group of contaminants that have been targeted. Contaminants are usually present in the environmental samples at very low concentration levels (ng L-1) and, for this reason, solid phase extraction techniques are often used to isolate and pre-concentrate the organic compounds of interest.

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