This application note demonstrates a quantitative analysis of δ9-Tetrahydrocannabinol (THC) from a cannabidiol oil sample. The calibration curve yields a correlation coefficient R2 of 0.9997. Combining the low RSDs at 3.4% from 7 runs, the Pyroprobe is qualified for quantitative thermal extraction of THC.
Cannabidiol (CBD), derived from the cannabis plant, has a growing interest in nutraceutical and pharmaceutical industries. Similar in structure to psychoactive δ9-Tetrahydrocannabinol (THC) found in marijuana, non-intoxicating CBD is being credited with helping treat many medical issues. Diluted in hemp seed oil, CBD oil is a complex natural product, containing many volatile and non-volatile constituents. As demonstrated in an earlier application note1 , the Pyroprobe could be used to clarify constituents in CBD oil by first separating ingredients based on their volatility from thermal extraction, then pyrolyzing the non-volatile portion at higher temperature.
Due to the concern from public on distinguishing CBD products from marijuana, the Agriculture Improvement Act of 2018, Pub. L. 115-334, (the 2018 Farm Bill) was signed into law on Dec. 20, 2018, which states that cannabis products containing less than 0.3% (3 µg/µL) THC are exempted from controlled substances under federal law. To assist in law enforcement activities, this application note describes a novel approach to use a Pyroprobe and GC/MS to quantify the THC concentration from commercially available CBD products.
>> Download the Full Application Note as a PDF
Newsletters
Receive the latest analytical scientist news, personalities, education, and career development – weekly to your inbox.
