In this Application Note, we describe the design and operation of the new BioVOC-2™ breath sampler, and summarise the applications of this approach, which include clinical diagnostics, occupational health monitoring, and assessing exposure of the public to VOCs.
Breath provides a window into the health of the human body, and analysing the volatile organic compounds (VOCs) it contains can provide information on topics as diverse as the diagnosis of disease, the monitoring of metabolic stress, and exposure to toxic chemicals.
Various techniques are available to study these VOCs, but one of the simplest is direct capture of exhaled VOCs onto a sorbent-packed tube, with subsequent analysis by thermal desorption–gas chromatography–mass spectrometry (TD–GC–MS). In this application note, we describe the BioVOC-2™ device from Markes International, which is a low-cost, easy-to-use sampler that uses this approach to capture VOCs in breath.