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Comprehensive Toolkit for Pharmaceutical & CDMO Volatile Impurities Analyses


The characteristic flexibility, stability, high throughput, and fast time to report analytical results of the Syft Tracer TM next-generation SIFT-MS instrument apply across multiple headspace approaches for diverse matrices. This application note briefly summarizes the use of (1) dissolution, (2) multiple headspace extraction (MHE), and (3) the method of standard additions, then provides a guide for identifying the appropriate headspace approach for various matrices. For contract drug manufacturing organizations (CDMOs) and contract research organizations (CROs) with short or long sample runs on diverse volatiles and matrices, Syft Tracer TM provides a uniquely productive and cost-effective analytical solution.

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