Enhancing the performance of SPME and sorptive extraction for GC–MS using trap-based preconcentration
This study shows how GC–MS performance for the sampling of aroma compounds and off-odours in beverages can be enhanced by using techniques incorporating trap-based preconcentration. The first part of the study focuses on SPME, and how trapping and enrichment can improve peak symmetry, qualitative analysis and sensitivity. The second part of the study compares these methods against automated probe-based high-capacity sorptive extraction, which as well as being operationally robust, offers improved recovery for higher-boiling compounds and an extended analyte range.
contributed by Markes |
Introduction
As a readily-automated, fast, solvent-free technique, solid‑phase microextraction (SPME) has become widely adopted for a broad range of samples and applications, including analysis of foods and beverages, profiling of aromas and off-odours, as well as environmental, clinical and industrial investigations.
This application range is supported by a variety of SPME fiber phases (including PDMS, polyacrylate and multi-phase DVB/CAR/PDMS), which allow analyte selectivity to be optimised. However, workflows for conventional (‘direct’) SPME sometimes suffer from its limited sensitivity. This stems from the small volume of sorptive phase on the fiber (typically ~0.5 μL of PDMS), as well as from the relatively slow heating rate of commonly-used GC injection ports, resulting in broad peaks.
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