Enhancing the sensitivity of headspace analysis using large volume preconcentration (LVP) – Trace-level GC–MS analysis of VOCs in foods and beverages

In this application note, we show an increase in sensitivity for headspace analysis using a sample preparation technique called large volume preconcentration (LVP). This is particularly useful for the analysis of trace-level volatile organic aroma and flavour compounds in food and beverage samples. As an example, an orange juice was analysed by headspace extraction using the Centri® sample extraction and enrichment platform operating in headspace–trap mode. Inclusion of a multi-bed focusing trap within the system flow path enables a preconcentration step after sample introduction, allowing for the extraction of headspace sample volumes greater than the conventional 1 mL. Additionally, the ability to introduce multiple headspace volumes to the trap is demonstrated as an enrichment process prior to GC–MS analysis. This provides an incremental response for each compound and comparative data are supplied for single and multiple extractions.