Extraction of a Drugs of Abuse Panel from Human Urine Using Biotage® Mikro CX SPE Microelution Plates Prior to UPLC-MS/MS Analysis
contributed by Biotage |
This application note describes the extraction of mulitple drugs of abuse from human urine using Biotage® Mikro CX microelution plates, prior to LC/MS analysis.
The simple sample preparation procedure, based on a mixedmode/strong cation exchange extraction mechanism, delivers clean extracts and analyte recoveries mostly greater than 70% with RSDs lower than 5% for most analytes. Linearity of greater than 0.999 is achieved for all analytes from 1–1000 pg/mL.
Mikro plate extraction allows for very low elution volumes and enhanced workflow efficiency.
Read the full article now
Log in or register to read this article in full and gain access to The Analytical Scientist’s entire content archive. It’s FREE!
Or register now - it’s free!
You will benefit from:
- Unlimited access to ALL articles
- News, interviews & opinions from leading industry experts
- Receive print (and PDF) copies of The Analytical Scientist magazine