Extraction of Epinephrine, Norepinephrine and Dopamine from Human Plasma Using EVOLUTE® EXPRESS WCX Prior to LC-MS/MS Analysis
contributed by Biotage |
Introduction
Catecholamines are biomarkers used for the detection of diseases such as hypertension, pheochromocytoma and neuroblastoma. The main target analytes are dopamine, epinephrine and norepinephrine (see Figure 1. for details), which are traditionally analyzed using liquid chromatography with electrochemical detection.
Log in or register to read this article in full and gain access to The Analytical Scientist’s entire content archive. It’s FREE!