FCR Affinity Chromatography - A New Approach to Assess Glycan Profiles During Cell Line Screening and Upstream Development

contributed by Tosoh | 11/10/2020

In cooperation with UGA Biopharma

Fc-glycans of therapeutic antibodies are known to play an important role in the recognition of antibodies by the FcγIIIa receptor. Accordingly, Fc receptor affinity-based separation is also correlated to the N-glycan profile. The TSKgel^® FcR-IIIA-NPR affinity chromatography column uses an Fc receptor modified by site-directed mutagenesis to create a ligand with greater stability.

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