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Fields & Applications Mass Spectrometry, Proteomics, Translational Science

High-throughput quantitative proteomics using Zeno SWATH data-independent analysis (DIA) and the Evosep One system

Analyzing large sample cohorts is critical when performing translational or biomarker research. To meet the sample introduction demands of high-throughput proteomics, the Evosep One system (Evosep) has been developed a standardized platform with preset methods. But faster chromatography quickly overwhelms traditional data dependent acquisition (DDA). Here using Zeno SWATH DIA – a data independent acquisition strategy, the combination of the Evosep One system and the ZenoTOF 7600 system was investigated for fast quantitative proteomics.

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