HPLC Analysis of SARS-CoV-2 drug Remdesivir and its active metabolite GS-441524 using YMC-Triart C18

contributed by YMC | 07/19/2021

Remdesivir and GS-441524 are antiviral drugs that have been examined for the treatment of COVID-19 caused by SARS-CoV-2 (severe acute respiratory syndrome coronavirus 2). Remdesivir is a nucleotide analogue inhibitor that can inhibit the replication of animal and human coronaviruses. Since it is a prodrug it needs to be metabolized into a pharmacologically active metabolite.

Log in or register to read this article in full and gain access to The Analytical Scientist’s entire content archive. It’s FREE!

Email*

Choose a password

I have read and understand the Privacy Notice *

Stay up to date with our other newsletters and sponsors information, tailored specifically to the fields you are interested in

Receive communication from The Cannabis Scientist I want to stay up to date with the Mass Spectrometry field

When you click “Subscribe” we will email you a link, which you must click to verify the email address above and activate your subscription. If you do not receive this email, please contact us at [email protected].
If you wish to unsubscribe, you can update your preferences at any point.

Characterization of MAbs Using FcR-Affinity and HILIC-MS

06/16/2022 | Contributed by Tosoh

Multi-residue Method Development using Agilent 6475 LC/TQ

06/08/2022 | Contributed by Agilent Technologies

Fast HILIC Analysis of Hydrophilic Dipeptides

05/30/2022 | Contributed by YMC

Fields & Applications Pharma & Biopharma

Quantify Viral Vector Attributes with Light Scattering

03/01/2022 | Sponsored by Wyatt Technology

Fields & Applications Pharma & Biopharma

Preparing for Pharma Analysis and QC in 2022 and Beyond

01/12/2022 | Sponsored by Merck

Fields & Applications Metabolomics & Lipidomics

Positional determination of the double bonds in fatty acyl chains of phospholipids using the EAD capabilities of the Zeno TOF 7600 system

12/13/2021 | Sponsored by SCIEX

Techniques & Tools Mass Spectrometry

Bullseye!

06/22/2022 | Jeff Zonderman | 4 min read

Techniques & Tools Spectroscopy

The Decade’s Biggest Spectroscopy Breakthroughs

12/28/2021 | James Strachan

Techniques & Tools Mass Spectrometry

Diving Deeper into the Depths of the Proteome

06/28/2022 | Sponsored by SCIEX | 5 min read

Business & Education Professional Development

The Top 40 Under 40 Power List 2022: Nominations Are Open!

05/09/2022 | James Strachan

Techniques & Tools Mass Spectrometry

Qual and Quant MS: The Perfect Marriage

02/25/2015 | Rich Whitworth