HPLC Analysis of SARS-CoV-2 drug Remdesivir and its active metabolite GS-441524 using YMC-Triart C18

contributed by YMC | 07/19/2021

Remdesivir and GS-441524 are antiviral drugs that have been examined for the treatment of COVID-19 caused by SARS-CoV-2 (severe acute respiratory syndrome coronavirus 2). Remdesivir is a nucleotide analogue inhibitor that can inhibit the replication of animal and human coronaviruses. Since it is a prodrug it needs to be metabolized into a pharmacologically active metabolite.

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