Correlation of FcR Affinity Chromatography with Glycan Pattern and ADCC Activity of a Therapeutic Antibody

contributed by Tosoh | 04/14/2020

Tosoh Bioscience introduced TSKgel FcR-IIIA-NPR a new HPLC affinity column based on recombinant FcγIIIa receptor, a key player in antibody-dependent cell-mediated cytotoxicity (ADCC). FcγRIIIa affinity chromatography allows fast evaluation of biologic activity and glycoform patterns of antibodies.This innovative and robust method can provide valuable information during cell line selection, upstream optimization, or quality control of therapeutic antibodies.

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