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Why is GOLD-grade glass quality important when detecting low concentrations of analytes?

Have you ever thought about the quality of your glass vial? If not, this study will give you an overview, why glass quality is so important, especially when you want to detect small concentrations or certain structures of analytes. In this study drugs (e.g. Doxepin, Clomipramin, Bromperidol (containing trisubstituted N-atoms = tertiary amines and other TCA´s) have been investigated in serum in order to see the effects of certain glass qualities. The results are reported by reproducibility data using different types of 2 mL autosampler glass vials.

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