Ion-Pair ReversedPhase Analysis of an Oligonucleotide Ladder Standard with Avantor® ACE® Oligo

contributed by Avantor | 08/14/2020

Oligonucleotides are short lengths of DNA/RNA which are increasingly being used as therapeutic agents for the treatment of genetic disorders and cancers.

With oligonucleotide treatments, it is possible to synthesize a single-strand of DNA/RNA which has a complementary sequence to a disease-causing gene. Once this therapeutic DNA sequence has bound to the target gene in the body, the gene is deactivated. This method of treatment is known as antisense therapy

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