Method Development for Analysis of Amyloid Beta Proteins
contributed by YMC |
Amyloid β (Aβ) are peptides of 36–43 amino acids that are derived from the amyloid precursor protein (APP) by cleavage with β- and γ- secretase. Aβ are the main components of amyloid plaques and therefore crucially involved in Alzheimer’s disease. The biological function of Aβ is still unexplained, but they are claimed to be neurotoxic as they form extracellular deposits in the brain and so can harm the cellular membrane.
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