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Molecular Weight Determination of VLPs Using LENS3 Multi-Angle Light Scattering Detector

Viruses and virus like particles (VLPs) are multimeric protein structures that mimic native viruses but are non-infectious. VLPs are subjects of interest, as their potential continues to grow as candidates in new vaccines and gene therapy products. For example, commercially available VLP-based vaccines are available for Hepatitis B and human papillomavirus. Robust analytical techniques are needed to not only ensure quality of final products but provide data for informed decision-making during the development process.

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Related Application Notes

Analysis of Bevacizumab (Avastin®) by SEC-MALLS

| Contributed by YMC

Light Scattering for Determination of Molecular Weight and Radius of Gyration

| Contributed by Tosoh

Expanding the Boundaries of Light Scattering Detection

| Contributed by Tosoh

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