Preparative Purification of Ibuprofen and Related Substances by Nexera UFPLC

contributed by Shimadzu | 11/30/2023

Preparation and purification by liquid chromatography is a widely-used technique in the pharmaceutical, food, and chemical industries for drug synthesis, finding effective compounds in natural products, and for structural analysis of unknown trace compounds. Nexera UFPLC*1 enables substantial labor savings in preparative purification by automating not only the fractionation of the target compound but also related processes such as concentration, purification, and recovery. This article describes an example of preparative purification of a mixed sample of the pharmaceutical ibuprofen and its analogues using Nexera UFPLC (Fig. 1).

Log in or register to read this article in full and gain access to The Analytical Scientist’s entire content archive. It’s FREE!

Email*

Choose a password

I have read and understand the Privacy Notice *

Stay up to date with our other newsletters and sponsors information, tailored specifically to the fields you are interested in

Receive communication from The Cannabis Scientist I want to stay up to date with the Mass Spectrometry field I want to stay up to date with the Spectroscopy field

When you click “Subscribe” we will email you a link, which you must click to verify the email address above and activate your subscription. If you do not receive this email, please contact us at [email protected].
If you wish to unsubscribe, you can update your preferences at any point.