As method sensitivity in LCMS instrumentation has improved, the need to reduce the extraction and leaching of chemicals contained in the membranes of the filters used for sample preparation becomes increasingly vital.
The Acrodisc® MS from Pall Laboratory was designed to address this, and is certified for low extractables in sensitive LCMS methods, to produce a quality syringe filter that does not sacrifice on results quality or consistency.
Detailed in this application note is a test conducted on the Acrodisc MS, and two other PVDF and Hydrophilic PTFE membrane filters.