Sensitivity boost - comparison of electrochemical and refractive index detection for sugar analysis

Summary

The determination of carbohydrates in food and other matrices is always a topic of high concern. The exact determination of sugar content is not only essential when thinking of foods targeted to diabetics. Such sensitive analytical methods are also interesting to manufacturers of sugar based pharmaceutical products or for research projects in the field of carbohydrates. Here, we compare the HPLC analysis with electrochemical detection (ECD) versus refractive index detection (RID) for the determination of glucose, sucrose, and arabinose.