Sangeeta Tanna

Sangeeta Tanna holds a PhD in pharmaceutics in the development of an artificial pancreas. Her expertise and research interests lie in the bioanalysis and drug delivery fields. This has led to the development of micro-analytical methodologies for the determination of therapeutic drugs from dried blood spots (DBS) based on LC-MS and LC-MS/MS studies for a range of clinical applications. This research was awarded the Royal Society of Chemistry Analytical Methods Prize in 2010. Applications of this work to patient care include improved medication for babies and people with cardiovascular diseases.

Content by Sangeeta Tanna:

Fields & Applications Sample Preparation

Confronting Concerns

04/16/2013 | Sangeeta Tanna, Graham Lawson

With many potential benefits, it is easy to understand the drive to develop systems and methods acceptable to the regulatory authorities.

Fields & Applications Genomics & DNA Analysis

Principal Drivers for DBS Research

04/15/2013 | Sangeeta Tanna, Graham Lawson

It is now recognised that regarding a child as a scaled down adult to calculate a medicine dose may not be appropriate.

Fields & Applications Mass Spectrometry

Dried Blood Spot 101

04/15/2013 | Sangeeta Tanna, Graham Lawson

Introduced by Robert Guthrie in the 1960s, dried blood spot (DBS) sampling involves taking small drops ... of blood from either a finger prick (or heel prick in neonates) and depositing them on specially manufactured absorbent card where they are allowed to dry. Once dry, DBS cards can be readily transported by post for analysis since the components of the blood remain unchanged for several days, even at room temperature. For analysis, a portion of the blood spot is removed from the card and placed in a solvent to extract the analyte(s) of interest.

Fields & Applications Mass Spectrometry

Spot On

04/15/2013 | Sangeeta Tanna, Graham Lawson

Dried Blood Spot (DBS) sampling is being adopted in drug development, paediatric healthcare, and, more recently, patient compliance.