Yoshio Okamoto

Yoshio Okamoto is a Professor Emeritus at Nagoya University, Japan. In 1979, Okamoto’s group obtained the first helix-sense- selective polymerization using triphenylmethyl methacrylate as a monomer and (–)-sparteine-n-BuLi complex as an initiator. The one-handed helical polymer (PTrMA) exhibited unexpected high chiral recognition ability. In 1982, PTrMA-coated silica gel was commercialized as the first synthetic polymer- based chiral column. In 1984, his group discovered excellent chiral recognition abilities with cellulose triphenylcarbamate and, in 1986, its 3,5-dimethyl derivative, which has been commercialized as Chiralcel OD. Okamoto’s group also reported amylose 3,5-dimethylphenylcarbamte (Chiralpak AD) in 1987. The latter two, OD and AD, are still some of the most popular chiral stationary phases used in HPLC and SFC.

Content by Yoshio Okamoto:

Techniques & Tools Liquid Chromatography

Gurus of Chiral Separations

01/20/2015 | Christopher J. Welch, Yoshio Okamoto, Bernard Testa, Wolfgang Lindner

In Lewis Carroll’s 1871 novel, Through the Looking-Glass, Alice suggests to her black kitten, “Perhaps Looking-Glass milk isn’t good to drink...” And though our four gurus don’t attempt to predict the potability of milk from a mirror world, they keenly address the broader significance of chirality, the major milestones in chiral analysis, and where the field is heading.

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12/12/2012 | Charlotte Barker, Pat Sandra, Marcus Lippold , Rich Whitworth, Karen Trentelman, John K. Delaney, Yuriko Jackall, Michael Swicklik, Ana Martins, Petria Noble, Koen Janssens, Caroline West, Sarah Maurer, Donald Chace, Giuseppe Petrucci, Greg Miller, Robert Kraus, Sebastian Pantò, Han van Krieken, Joanna Cummings, Steven (Steve) Schultz, Jonathan Sweedler, Sonja Masselter, Magnus Jezussek, Despo Louca, Michèle Lees, Bruce McCord, Georgios Theodoridis, Tim Causon, Deirdre Cabooter, Steven Lehotay, Torsten Schmidt, William Tindall, Thomas Jocks, Vincenzo Palleschi, Abhijit Ghosh, Christian Wenz, Tomoyoshi Soga, Rob Haselberg, Norman (Norm) Dovichi, Michael Knierman, Peter Schoenmakers, Marcel Florin Musteata, Tiemin Huang, Ryan Sasaki, Nicholas Snow, Rob Haselberg, Frank Vanhaecke, William Tobin, Clifford Spiegelman, Taco van der Maten, Constantine Stalikas, Jörg Feldmann, Dietmar Knopp, Michael Snyder, Vicki Blazer, Bryn Flinders, Kévin Contrepois, Susan D. Richardson, Vince Remcho, Lisa Holland, Silvia Bruni, Andrew Palmer, Theodore Alexandrov, Heinz Siesler, Rudolf Kessler, Elyssa Litchfield, Peter James, Michael Lämmerhofer, Philip Marriott, Joshua Coon, Jack Cochran, Fabrice Gritti, Gert Desmet, James Jorgenson, Monika Dittman, Mary Wirth, Mustafa Culha, Mirek Macka, Zuzana Gajdosechova, Rainer Bischoff, Scott Phillips, Richard C. King, Eric Francotte, Mark T. Stauffer, Andrew Dix, Kimberly Moser, Lothar Brecker, Thomas Annesley, Sebastiaan Eeltink, Frantisek Svec, Nobuo Tanaka, Steven Olde Damink, Ron M. A. Heeren, Jeremy Nicholson, Joshua Windmiller, Robert Thomas, Brad Lord, Wolfgang Lindner, Bernard Testa, Yoshio Okamoto, Christopher J. Welch, David Matthew, Gareth S. Dobson, John DeHaan, Eva Tyteca, Dennis Åsberg, Purnendu Dasgupta, Jeroen Kool, Willem Jonker, Paul G. Stevenson, George Scott, Joachim Weiss, Markus Läubli, Paul Haddad, Steve Thomas, Victoria Samanidou, Bob Blackledge, Lee DesRosiers, Claas Wagner, Kim H. Esbensen, Bert Pöpping, Olaf de Groot, Martin Gilar , Anne Francois Aubry, Henry Nowicki, Sergio Nanita, André de Kok, Lutz Alder, Finbarr O’Regan , Henk van 't Klooster, Ewa Szymańska, Ulrich Panne, Xiaojiang Xie, Eric Bakker, André de Villiers, Jody Dunstan, Elizabeth Thomas, Aydogan Ozcan, Bayden Wood, Jack Cochran, Chuck Henry, John Volckens, David Cate, Stephanie Vine, Christopher R. Harrison, Ian Jardine, Ben Potenza, John A. McLean , Bill Anderson, Lawrence “Larry” Mason, W. Franklin Smyth, Volker Deckert, Peter Griffiths, Gary Hieftje, Justin Bueno, Igor Lednev, Curtis Marcott, Craig Prater , Hans-Gerd Janssen, Jean-François Focant, Ashley Sage, George M. Whitesides, Alberto Mantovani, Juan Muñoz-Arnanz, Lourdes Ramos, Ron van der Oost, Annemieke Kolkman, Juliane Hollender, Werner Brack, Debdulal Roy, Alejandro Cifuentes, Joachim Pleil, Terence Risby, Nick Kim, Iestyn Armstrong-Smith, Herman Ram, Douwe de Boer, Rick Russo, Reinout Raaijmakers, Albert Heck, Miguel de la Guardia Cirugeda, Robert Trengove , Axel Walch, Ron M. A. Heeren, Joeri Vercammen , David C. Muddiman, Jeremy Barry, Kenneth P. Garrard, Guillaume Robichaud, Kim H. Esbensen, Alexander Bünz, Andrew Ward, John Yates, Barry Karger, Christian Huber, Dev Kant Shandilya, Adrian Stevens, André Deelder, Jon Platt, Konstantin Choikhet, Imre Molnár, Alexander Makarov, Michel Nielen, Yolanda Pico, Michele Suman, Rudolf Krska, John Coates, Peter Gorst-Allman, Jayne de Vos, Eric Lesellier, Davy Guillarme, Isabelle François, Melanie Voigt, Anika Gold, Christina Blaesing, Timo Hoelscher and Martin Jaeger, Joan LLuis-Vives Corrons, Emily Hilder, Richard Gallagher, Mike Grayson, Dave Strong, Lutgarde Buydens, Giuseppe Astarita, Yaroslav Faybishenko, Frank Neely, E. Neil Lewis, Jaap de Zeeuw, Frank van Geel, Amanda Hummon, Norm Dovichi