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The optimization and scale-up of high shear granulation

sponsored by Malvern Panalytical

The first step in producing optimized granules for tableting is the wet granulation itself which produces agglomerates that range from a few hundred microns to several millimeters in diameter. These are typically wet milled prior to drying in a fluidized bed dryer. Subsequent milling of a dried particles produces a closely specified granular feed for the tablet press.

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