Exceed in biopharma, metabolomics, proteomics, and structural biology applications with Orbitrap Excedion Pro mass spectrometers.
Orbitrap Excedion Pro hybrid mass spectrometers deliver enhanced sensitivity, dynamic range, and fast and sensitive electron-based fragmentation to transform everyday analysis into exceptional results.
Welcome to the future of mass spectrometry. Enhance your research and achieve groundbreaking discoveries with Thermo Scientific™ Orbitrap™ Excedion™ Pro hybrid mass spectrometers, the next generation of mass spectrometry.
With enhanced sensitivity and dynamic range, the Standard Model is ideal for advanced applications in metabolomics, lipidomics, proteomics, translational research, and structural biology while the BioPharma Edition is tailored for the demanding requirements of the biopharmaceutical industry. Both models offer innovative features that surpass the capabilities of the previous Thermo Scientific™ Orbitrap Exploris™ 480 mass spectrometer.
Orbitrap Excedion Pro MS - brochure
Designed for biopharma, metabolomics, proteomics and structural biology applications, Orbitrap Excedion Pro mass spectrometers deliver enhanced sensitivity, dynamic range, fast and sensitive electron-based fragmentation, and unique capabilities transforming everyday analysis into exceptional results. Explore the model and features that best suits your needs and unlock the full potential of your analytical workflows.
DownloadThe evolving role of mass spectrometry in proteomics research - case study
Learn how the Orbitrap Excedion Pro MS enhances sequence coverage for immunopeptidomics analysis. Dr. Albert Heck and his team discuss how the Orbitrap Excedion Pro MS with EThcD fragmentation boosts peptide sequence coverage, minimizes detrimental sequence gaps, and allows less error-prone immunopeptidomics, glycoproteomics, and de novo sequencing.
DownloadBridging global depth and targeted sensitivity for proteomic analysis - technical note
Discover how hybrid DIA powered by an adaptive retention time (adaptive RT) routine is helping scientists overcome critical proteomics research challenges by eliminating the compromises between comprehensive and targeted analysis. Comprehensive protein identification is achieved across a wide dynamic range while simultaneously obtaining precise and accurate quantitation of low-abundance targets.
DownloadComprehensive peptide mapping analysis of protein therapeutics - technical note
Find out how EThcD MS/MS peptide mapping on the next-generation Orbitrap Excedion Pro BioPharma hybrid MS achieves high protein sequence coverage, accurate identification and localization of low-abundant post-translational modifications (PTMs), and unambiguous differentiation of isomeric amino acids in a single LC-MS run.
DownloadIn-depth characterization of KADCYLA using fast and sensitive EThcD fragmentation - technical note
Antibody-drug conjugates (ADCs) have evolved into promising and efficient therapeutic agents for targeted chemotherapy in cancers. See how the outstanding performance of an Orbitrap Excedion Pro BioPharma hybrid mass spectrometer for in-depth characterization of KADCYLA, a lysine-linked antibody drug conjugate.
DownloadHigh-sensitivity host cell protein (HCP) analysis - technical note
Monitoring HCPs is an integral part of the biopharmaceutical manufacturing QA process to prevent adverse reactions from residual HCP impurities that co-purify with therapeutic proteins. See how the highly sensitive Orbitrap Excedion Pro Biopharma hybrid mass spectrometer coupled with the Thermo Scientific™ Vanquish™ Horizon UHPLC system addresses the challenge by identifying sub-ppm level HCPs.
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