Fast, Accurate Results in Pharmaceutical Testing with Kinetex™ Core-Shell Columns.
This collection of resources highlights how core-shell technology columns combined with pharmacopeia allowable adjustments can be utilised in a modern pharmaceutical laboratory to save time, solvent and money while remaining within the constraints of pharmacopeia monographs.
Core-shell technology columns have been shown to provide higher efficiency separation than corresponding fully porous columns of the same particle size. This increase in efficiency can be utilised to either enhance the resolution in the separation of complex mixtures, or through using an appropriate column with a shorter length a faster separation can be achieved.
Case Study: Meeting System Suitability using <621> Allowable Adjustments for USP Abacavir and Lamivudine Tablets Assay
Abacavir and Lamivudine treat HIV with other medications. The USP monograph describes using an L1 column for separation. This study shows that the XTERRA® 3.5 µm MS C18 column can be replaced with either a Luna Omega 3 µm C18 or a Kinetex 2.6 µm EVO C18 column, both alternative L1 columns.
DownloadPh. Eur. Monograph 1028: Metoprolol Tartrate and Related Substances with Ph.Eur. Method Modernization
This application note demonstrates the potential method improvements that can be achieved within the allowed adjustments of chromatographic conditions. A Luna C18(2) and a Kinetex C18 column were used for evaluating the related substances method, within the allowable adjustments published by the European Pharmacopeia, Chapter 2.2.46.
DownloadKinetex Core-Shell LC Column Guide
This guide showcases the award-winning core-shell technology that combines speed, efficiency, and robustness, making it ideal for pharmaceutical applications. The core-shell particle morphology minimizes band broadening, resulting in sharper, more distinct peaks. Explore real-world pharmaceutical applications demonstrating the versatility and high performance of Kinetex columns.
DownloadAllowed Adjustments Ph Eu
Easily determine the allowable adjustments that can be made to European Pharmacopoeia (Ph Eu) methods and find the right column for your method.
DownloadAllowed Adjustments USP
Quickly view the allowable adjustments that have been outlined by the United States Pharmacopeia (USP) and then select the proper Phenomenex column for your monograph using this simple guide.
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