Functional Characterization of CAR-T Cells

Novel immunotherapies, including bispecific antibodies, tumor infiltrating lymphocytes (TILs), and chimeric antigen receptor (CAR) T cells, have been developed to enhance T cell responses against cancer.

There is a need for the development of robust and relevant strategies, to monitor novel therapeutics for sufficient activation and anti-tumor efficacy. High-Throughput Screening (HTS) by Cytometry can add value when developing and characterizing T cell therapies, at multiple stages in the development and expansion of cell products and can be applied to multiple cell types.

White Paper - Phenotypic and Functional Characterization of CAR-T Cells with High-Throughput Screening by Cytometry and Live-Cell Analysis

Data examples shared in this whitepaper demonstrate how the use of both live-cell analysis and HTS by Cytometry can add value when developing and characterizing T cell therapies.

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Application Note - Characterization of T Cell Activation and Function in Cancer Immunotherapy Using High-Throughput Cytometry

This application note demonstrates the value of using High-Throughput Screening Cytometry in conjunction with validated Human T Cell Activation Kits, to assess immune cell phenotype and function during the development of antibody-mediated and cell based cancer therapies using minimal sample volumes.

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iQue 3 Brochure

The iQue® 3 HTS Cytometer is designed for high-throughput screening workflows. With a focus on speed and ease of use, it delivers high quality results in the time it takes to enjoy a coffee break. Featuring a patented sampling method, enables continuous plate loading through integration with any automation system.

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iQue 5 Brochure

iQue® 5 Truly Fast. Simply Effortless. High-Throughput Screening (HTS) by Cytometry, recognized for effortless operation to empower every user. Provides our most powerful screening capabilities for modern applications, complete with enhanced software features and simplified extended operation for maximum data generation.

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