Resolvex® A200: Automated Precision for Biopharma LC-MS Sample Preparation
Automate sample preparation for various scales, volumes and samples without sacrificing consistency.
What if one instrument could bring consistency to every column-based workflow? From DNA purification to peptide cleanup to antibody isolation, Resolvex A200 transforms how scientists prepare their samples for LC-MS. Customize pressure profiles, solvent dispensing and elution steps to conduct sample prep at the touch of a button with unmatched reproducibility and control.
The A200 has proven its value in plasmid extraction, antibody isolation and peptide digestion, but these are only a few examples of what Resolvex A200 can do. Wherever precision, scalability and hands-free efficiency matter, the A200 is a robust, benchtop platform to fit virtually any lab.
Semi-automated giga column plasmid DNA extraction using positive-pressure processing.
Extracting large volumes of supercoiled plasmid DNA from bacterial cultures is needed for various downstream biology applications. Automating this process with positive pressure enables reproducible extractions for consistent analyses.
DownloadScalable and automatable benchtop protein A based monoclonal antibody purification using AffinEx™ solid phase extraction columns with Resolvex® A200.
Monoclonal antibodies are a main force behind the search for novel, targeted therapeutics. Affinity capture combined with positive pressure processing allows for automated and scalable mAb cleanup with both logistical and cost-effective advantages.
DownloadRapid proteomics sample preparation with on-column digestion
This application note details the combination of Resolvex A200 and Narrow Bore Extraction™ (NBE) for even less manual handling steps. Ideal for bottom-up proteomics workflows, the on-column digestion capabilities of NBE further enhance reproducibility and consistency.
DownloadViral RNA extraction using the Resolvex A200 supports large-scale SARS-CoV-2 testing
The need for RNA purification became apparent as COVID-19 spread. This, coupled with the need for reliable analysis, made the Resolvex A200 an ideal solution for high-quality sample prep. A workflow was promptly designed with the Zymo Quick-RNA Viral 96 kit to efficiently and reliably extract viral RNA.
DownloadLCMS analysis of pharmaceutical analytes in plasma using Atlas extraction consumables.
In this poster, a generic workflow for extracting pharmaceutical analytes using Resolvex A200 and Atlas HLB sorbent is described. This data effectively compares the Resolvex platform for sample preparation against well-established and commonly used solutions.
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