Unlock the Future of Real-Time Analysis with Syft Technologies

Welcome to Syft Technologies, the global leader in real-time trace gas analysis. Our cutting-edge Selected Ion Flow Tube Mass Spectrometry (SIFT-MS) technology offers unmatched reproducibility, sensitivity, and speed, empowering industries to meet their most demanding analytical challenges. From pharmaceutical nitrosamine screening and semiconductor contamination monitoring to environmental compliance and advanced solvent analyses, Syft delivers transformative solutions. Explore the Syft Tracer for versatile real-time detection, Syft Explorer for precision in semiconductor applications, and groundbreaking insights like the 2025 Alternative Solvents Tech Note. Whatever your field, Syft enables unparalleled performance, ensuring faster results, deeper insights, and cleaner processes. Join the leaders who trust Syft to redefine trace analysis.

SyftTracer Brochure

Syft TracerTM is the latest advancement in real-time, direct injection mass spectrometry (MS) built to solve the most difficult analytical challenges faced within a variety of industries and applications. This advancement to SIFT-MS delivers trace-level detection sensitivity, unparalleled performance stability, superior selectivity, and highly reproducible, quantitative data. Syft Tracer is optimized for high-throughput environments where continuous operation is the standard. Never miss a product or environmental contamination event again.

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Syft Tracer Pharm11 Brochure

Learn about the world's only 21 CFR Part 11 compliant real-time mass spec, Syft Tracer Pharm11. It is a high-throughput solution for compliant pharma and CDMO workflows.

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Syft Explorer Brochure

Syft Explorer is a comprehensive solution for making real-time mass spec measurements anywhere on-site. It includes next-gen SIFT-MS, onboard clean dry air, and automatic power management bundled in a mobile format. Never miss a contamination event again!

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SIFT-MS: A Highly Reproducible Real-Time Trace Gas Analysis Technology

SIFT-MS instruments show exceptional reproducibility. By comparing standardized analytical methods on multiple instruments, it demonstrates high consistency in trace gas quantitation with 95% confidence intervals below 21% for the Syft Tracer and 38% for legacy devices. The findings emphasize Syft's commitment to advancing reliable, real-time analysis solutions for diverse applications.

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Rapid and Quantitative Screening of Nitrosamines in Drug Products Using Headspace-SIFT-MS

This study demonstrates that headspace-SIFT-MS meets United States Pharmacopeia (USP) criteria for six nitrosamines, achieving low limits of quantitation (0.06 ppm for NDMA and 0.03 ppm for NDEA) even in complex drug matrices. With high recovery rates and significant reductions in solvent usage, consumables, and operational complexity compared to traditional chromatographic methods, the Syft Tracer Pharm11 solution is an efficient screening tool for nitrosamines and volatile impurities.

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Real-Time Measurement of EPA Regulated HON Compounds and Environmental Pollutants Using SIFT-MS

This application note highlights the capabilities of SIFT-MS for real-time measurement of EPA-regulated Hazardous Organic NESHAP (HON) compounds. By achieving sub-pptV method detection limits, it demonstrates the technology's suitability for regulatory fenceline monitoring and rapid source identification.

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Progress with Alternative Solvents for SIFT-MS: 2024 Update

Explore advancements in utilizing alternative solvents for SIFT-MS. This tech note introduces three new solvents—acetonitrile, N,N'-dimethylpropyleneurea (DMPU), and propylene glycol (PG)—and highlights the enhanced sensitivity and applications of existing solvents like triacetin. The findings demonstrate significant benefits in analyzing diverse VOCs while addressing challenges in method development.

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