Finding Osteoarthritis’ Missing Link with Mass Spectrometry
Mass spectrometry may help identify reliable biomarkers for osteoarthritis
Olivia Gaskill |
Osteoarthritis (OA) is one of the most common joint disorders – but its mechanisms are still not fully understood and existing biomarkers lack reliability and sensitivity. This makes it difficult for clinicians to prescribe targeted treatments – a problem University of South Australia researchers are dedicated to solving.
Covering a 20-year period, they reviewed research that used mass spectroscopy imaging (MSI) to map complex sugars associated with cartilage damage in OA (1). By identifying these molecular mechanisms, the team hope to explain why cartilage degrades at different rates and potentially identify diagnostic biomarkers.
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