This Thermo Scientific™ customer application note demonstrates a solid, generically applicable workflow for bioorganic, medicinal, and synthetic chemists and other researchers. With Thermo Fisher Scientific now offering more column choices for preparative LC, scientists can easily scale up their chromatography using their preferred Thermo Scientific column brands. The Thermo Scientific™ Hypersil GOLD™ C18 column used enabled the separation and resolution of four diastereoisomers, which are typically hard to resolve, in both the analytical and preparative formats. The Hypersil GOLD C18 proprietary ligand chemistry offers a robust, easy to scale up solution for more advanced purifications.
