
High Performance Anion-Exchange Chromatography (HPAEC) is the most powerful analytical technique for carbohydrate analysis due to its ability to separate all classes of alditols (polyols), aminosugars, mono-, oligo- and polysaccharides including glycans, according to structural features such as size, composition, anomericity and linkage isomerism.
Antec Scientific developed a novel pellicular anion-exchange stationary phase called SweetSep AEX. The phase is based on highly uniform monodisperse 5 µm resin particles of crosslinked poly(divinylbenzene-co-ethylvinylbenzene) copolymer. The particles are furthermore coated with quaternary amine functionalized nanoparticles.