Tip-on-Tip technology combines a bottom Filtration tip with a top wide bore conductive tip. The top tip aspirates a sample solution, fits into the Filtration tip, and dispenses the sample through the Filtration tip providing a clean, particulate-free solution. Filtration tips are available in a variety of porosities.
ToT Filtration has broad applicability, including forensic, clinical, bioanalytical, organic synthesis and cannabis sample preparation. The methodology provides an automated alternative to traditional filtration/centrifugation. ToT Filtration is ideal for high-throughput online protein precipitation, b-glucuronidase removal, or any other application requiring particulate removal. Particulates can be removed down to less than 1 µm to prevent clogging of LC columns.
Download resources for INTip methods and applications.
