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The Analytical Scientist / App Notes / 2014 / 11 HPLC Myths

11 HPLC Myths

04/23/2014

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Introduction

HPLC myths have been around since the early 1900’s. It’s about time you found out the whole truth!

Phenomenex logo
From the one about the handsome architect who started a chromatography company to the one about the best silica coming from the beaches of Fiji. Here at Phenomenex we believe that you deserve the truth!
MYTH #1
Fully porous silica is just as good as Core-Shell Technology. No Way! Kinetex Core-Shell Technology produces increased efficiencies over traditional columns on the market, yielding remarkable chromatographic resolution, higher peak capacities, and greater sensitivity, so you can get the most out of every HPLC analysis.
AppNote-04614-IMG1
MYTH #2
One core-shell particle size is all that exists for HPLC. While other column manufacturers add to this myth, we listened to your needs and designed and manufactured two Kinetex core-shell particles to cover methods on your HPLC systems.
Kinetex® 5 μm
  • Replace 3 and 5 μm fully porous columns for better performance at low 5 μm backpressures
  • Enhance LC/MS methods and column lifetime without small particle band broadening concerns
  • Easily achieve high efficiency preparative LC methods
AppNote-04614-IMG2
Kinetex® 2.6 μm
  • Save time and money with smaller, high performance columns
  • Use HPLC/UHPLC versatility to upgrade methods
  • See more peaks with sub-2 μm like performance on HPLC and UHPLC systems
AppNote-04614-IMG3
>> Download the full Application Note as PDF

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