Key Words
Accucore XL C8, solid core, core enhanced technology, triazines, simazine, simetryn, atrazine, prometon, ametryn, propazine, prometryn
Abstract
This application note compares the performance of the solid core Thermo Scientific Accucore XL C8 4 μm HPLC column with that of a fully porous 5 μm traditional HPLC column for the analysis of triazines under gradient mobile phase conditions.

Introduction
Based on Core Enhanced TechnologyTM using 4 μm solid core particles, AccucoreTM XL HPLC columns allow users of conventional HPLC methods to enjoy performance far beyond that of columns packed with 5 μm or even 3 μm fully porous particles. Very high separation efficiencies using standard HPLC instruments and conditions provide increased peak resolution and lower limits of detection. An ultra-stable packed bed results in exceptionally robust columns that demonstrate excellent retention and response reproducibility. Simazine, simetryn, atrazine, prometon, ametryn, propazine and prometryn belong to the triazine class of compounds. They are commonly used as herbicides. This application note demonstrates the improvement in efficiency, sensitivity and resolution for the analysis of seven triazines on an Accucore XL C8 4 μm HPLC column compared to a conventional 5 μm fully porous column using the same experimental conditions.