Introduction
The quantitative determination of the catecholamines Norepinephrine, Epinephrine, and Dopamine in urine and plasma is the preferred analytical method for initial diagnosis of several rare cancer tumor diseases in the body. Higher than normal levels of catecholamines in plasma and urine typically indicate the presence of tumors such as pheochromocytoma or ganglioneuroma. The Antec Scientific ALEXYS Clinical Analyzer offers fast and accurate analytical results for routine analysis of catecholamines, metanephrines and other metabolites such as VMA, HVA and 5-HIAA.
Summary
For the analysis of catecholamines and their metabolites in urine or plasma, the ALEXYS™ Clinical Analyzer based on HPLC with electrochemical detection (LC/ECD) provides a robust and sensitive method. The ALEXYS Analyzer is compatible with all major clinical kits for sample preparation and analysis to assure standardized catecholamines analysis. In Part I of this application note the analysis of chatecolamines in urine is described, and in Part II the analysis in plasma.
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