Early diagnosis plays a pivotal role in the effective treatment of diseases, particularly in oncology. However, the absence of apparent clinical symptoms and the limitations of conventional screening methods present significant challenges. To address this gap, medical science is exploring innovative diagnostic platforms, among which liquid biopsy has emerged as a promising technique. Introduced initially to detect circulating tumor cells (CTCs) in the bloodstream, liquid biopsy now encompasses a broader range of body fluids, including cerebrospinal fluid, saliva, pleural effusion, and most notably, urine.
Why Urine?
Urine offers a unique window into human health. As a biological fluid that is readily obtainable through non- invasive methods and widely accepted by patients, urine is increasingly being recognized for its diagnostic potential. It reflects the metabolic state of various organs and can indicate both inflammatory and neoplastic processes. With the presence of metabolites and biomarkers, urine becomes an ideal candidate for spectral analysis.
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